![]() ![]() Stock cultures were passaged at 2 to 3-day intervals. HepG2, MCF-7, HT-29 and CT-26 cells were grown and maintained in Dulbecco’s modified Eagle’s medium (DMEM) (Gibco, Thermo Fisher Scientific, Waltham, MA, USA), while Caco2 cells were grown and maintained in RPMI-1640 medium (Gibco, Thermo Fisher Scientific, Waltham, MA, USA), both supplemented with 10% fetal bovine serum (FBS) (Biosera, Boussens, France), penicillin (100 U/mL), and streptomycin (100 mg/mL) (Biosera, Boussens, France) and were incubated at 37 ☌ in a humidified atmosphere of 95% O 2 and 5% CO 2. Murine colon carcinoma CT-26 was kindly provided by V. The human hepatocellular carcinoma HepG2, the human breast adenocarcinoma MCF-7, the human colon adenocarcinomas Caco2 and HT-29 were obtained from the American Type Culture Collection (ATCC) (Rockville, MD, USA). ![]() fruit juice, and in parallel, the strong antioxidant potential implies that the plant could be further explored and exploited for its protective effect against oxidative damage. Thus, our findings raise interesting questions for further research on Cornus mas L. ![]() Although Cornelian cherry juice exhibited in vitro growth inhibitory effects against colon carcinoma cells, no tumor growth inhibition was observed in an in vivo experimental colon carcinoma model in mice following prophylactic oral administration of a daily dose of 100 μL juice for a period of 10 days. Cell viability was reduced by 40–50% following incubation of the cells with the highest concentration of the juice. The juice demonstrated significant antioxidant activity against the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) and modest antiproliferative potential against four human cancer cells lines and one murine: mammary adenocarcinoma MCF-7, hepatocellular carcinoma HepG2 and colon adenocarcinomas Caco2, HT-29, as well as murine colon carcinoma CT26. The fruits showed a high content of citric, malic, and succinic acid, in contrast to their juice, which had a low concentration of organic acids. fruit juice from Greece, as well as its antiproliferative properties in vitro and in vivo. In this report, we investigated the composition and the in vitro antioxidant capacity of Cornus mas L. (Cornelian cherry) is a flowering plant indigenous to Europe and parts of Asia, mostly studied for the antimicrobial activity of its juice. Please note that the “Buy it now” button skips this step and you won’t be able to add your message.Cornus mas L. Then if you wish to add a personalised message, there is a message box on the cart page. Simply select the preferred gift wrap packaging option above, then add product to Cart. Your gift will of course also include full growing instructions. ![]() We will also enclose a card – suitable for the occasion - with your own personal message. You can choose from 3 different colours: cherry red, pine green or antique gold, including a matching ribbon. We always recommend further research to learn the different ways in which the food source can be prepared and consumed.Īdd that personal touch with our bespoke gift wrapping service and choose from one of our luxurious but also natural looking wrapping papers. The intended main use of this plant is to grow food for human consumption. We have excellent quality, 15-20cm tall starter plants on offer.The whole plant diffuses an interesting, fruity scent – even when not in fruit. The fruit tastes sweet as well as acidic at the same time. In the late summer, countless bright red, soured cherry like fruits are formed which, when fully ripe are used for making a delicious sauce (similar to the traditional cranberry sauce) or jams. The Cornelian Cherry in particular gives your garden a glow during the drab, winter days. Before the leaves develop, masses of tiny, golden-yellow flowers appear like a golden mist around the bare stems. Cornus mas is a large ornamental fruit shrub or small fruit tree made up of dark green, shiny ovate leaves which turn a wonderful reddish purple during the autumn. ![]()
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